{ "_id": "6a17f3e7acfb0bcc41da80b7", "Package": "NMTox", "Type": "Package", "Title": "Dose-Response Relationship Analysis of Nanomaterial Toxicity", "Version": "0.1.0", "Authors@R": "c(person(given = \"Rahmasari Nur\",\nfamily = \"Azizah\",\nrole = c(\"aut\",\"cre\"),\nemail = \"rahma.azizah@uhasselt.be\"),\nperson(given = \"Geert\",\nfamily = \"Verheyen\",\nrole = c(\"aut\",\"ths\"),\nemail = \"geert.verheyen@thomasmore.be\"),\nperson(given = \"Sabine\",\nfamily = \"Van Miert\",\nrole = c(\"aut\",\"ths\"),\nemail = \"sabine.vanmiert@thomasmore.be\"),\nperson(given = \"Ziv\",\nfamily = \"Shkedy\",\nrole = c(\"aut\",\"ths\"),\nemail = \"ziv.shkedy@uhasselt.be\"))", "Maintainer": "Rahmasari Nur Azizah ", "Description": "Perform an exploration and a preliminary analysis on the\ndose- response relationship of nanomaterial toxicity. Several\nfunctions are provided for data exploration, including\nfunctions for creating a subset of dataset, frequency tables\nand plots. Inference for order restricted dose- response data\nis performed by testing the significance of monotonic\ndose-response relationship, using Williams, Marcus, M, Modified\nM and Likelihood ratio tests. Several methods of multiplicity\nadjustment are also provided. Description of the methods can be\nfound in\n.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.1.2", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-28 07:47:38 UTC", "User": "root" }, "Author": "Rahmasari Nur Azizah [aut, cre], Geert Verheyen [aut, ths],\nSabine Van Miert [aut, ths], Ziv Shkedy [aut, ths]", "Config/pak/sysreqs": "libicu-dev", "Repository": "https://rahmasarina.r-universe.dev", "Date/Publication": "2022-09-01 14:20:05 UTC", "RemoteUrl": "https://github.com/cran/NMTox", "RemoteRef": "HEAD", "RemoteSha": "53eb4029a0172baca548a96e60b6e9d7c02a6bc2", "MD5sum": "23d853f242a4529e0f575790ab87aa59", "_user": "rahmasarina", "_type": "src", "_file": "NMTox_0.1.0.tar.gz", "_fileid": "4ef1e5f7543ae4fd02c2268cab44ff752d9d2b5b88821dc0d77257c3ed5b3c25", "_filesize": 219356, "_sha256": "4ef1e5f7543ae4fd02c2268cab44ff752d9d2b5b88821dc0d77257c3ed5b3c25", "_created": "2026-05-28T07:47:38.000Z", "_published": "2026-05-28T07:51:03.795Z", "_distro": 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"job": 78246690689, "time": 86, "config": "windows-release", "r": "4.6.0", "check": "NOTE", "artifact": "7260467440" } ], "_buildurl": "https://github.com/r-universe/rahmasarina/actions/runs/26561726108", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/NMTox", "_commit": { "id": "53eb4029a0172baca548a96e60b6e9d7c02a6bc2", "author": "Rahmasari Nur Azizah ", "committer": "cran-robot ", "message": "version 0.1.0\n", "time": 1662042005 }, "_maintainer": { "name": "Rahmasari Nur Azizah", "email": "rahma.azizah@uhasselt.be", "login": "rahmasarina", "description": "", "uuid": 102209585 }, "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 2.10", "role": "Depends" }, { "package": "gridExtra", "role": "Imports" }, { "package": "dplyr", "role": "Imports" }, { "package": "ggplot2", "role": "Imports" }, { "package": "Iso", "role": "Imports" }, { "package": "tidyr", "role": "Imports" }, { "package": "forcats", "role": "Imports" } ], "_owner": "cran", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "rahmasarina", "count": 1, "uuid": 102209585 } ], "_userbio": { "uuid": 102209585, "type": "user", "name": "rahmasarina" }, "_downloads": { "count": 140, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/NMTox" }, "_searchresults": 0, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/NMTox.html", "manual.pdf" ], "_realowner": "rahmasarina", "_cranurl": false, "_releases": [ { "version": "0.1.0", "date": "2022-09-01" } ], "_exports": [ "adjPlot", "FrCtrl", "Frtab", "Frtab.sub", "Isoplot", "IsoPlot.nm", "IsoPval.nm", "Isotest", "IsoTest.nm", "nmplot", "nmplot.cat", "nmplot.n", "nmplot.ncat", "SplitData", "SubsetData" ], "_datasets": [ { "name": "geninvitro", "title": "Genetic toxicity in vitro dataset", "object": "geninvitro", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "name", "publicname", "supplier", "experimentID", "method", "studyprovider", "endpoint", "value", "unit", "celltype", "treatment", "exptimeunit", "exptime", "concentration_unit", "concentration", "concentration_ml_unit", "concentration_ml" ], "rows": 4161, "table": true, "tojson": true }, { "name": "nm400", "title": "NM-400 in vitro dataset", "object": "nm400", "class": [ "tbl_df", "tbl", "data.frame" ], "fields": [ "name", "publicname", "supplier", "experimentID", "method", "studyprovider", "endpoint", "value", "unit", "celltype", "treatment", "exptimeunit", "exptime", "concentration_unit", "concentration", "concentration_ml_unit", "concentration_ml" ], "rows": 253, "table": true, "tojson": true } ], "_help": [ { "page": "adjPlot", "title": "Plot the adjusted p-values, raw p-values and FDR level", "topics": [ "adjPlot" ] }, { "page": "FrCtrl", "title": "Create a frequency table of the control values", "topics": [ "FrCtrl" ] }, { "page": "Frtab", "title": "Generate the number of unique values, the list of unique values, or the number of observations of specified variable(s)", "topics": [ "Frtab" ] }, { "page": "Frtab.sub", "title": "Count the number of observations for each unique value of a variable on a subset of data", "topics": [ "Frtab.sub" ] }, { "page": "geninvitro", "title": "Genetic toxicity in vitro dataset", "topics": [ "geninvitro" ] }, { "page": "Isoplot", "title": "Create plot(s) of the observations, the sample means and the fitted isotonic regression curve", "topics": [ "Isoplot" ] }, { "page": "IsoPlot.nm", "title": "Create a plot of the observations, sample means and fitted isotonic regression curve for one nanomaterial", "topics": [ "IsoPlot.nm" ] }, { "page": "IsoPval.nm", "title": "Calculate p-values based on permutation for both increasing and decreasing ordered alternatives", "topics": [ "IsoPval.nm" ] }, { "page": "Isotest", "title": "Calculate the test statistics and p-values for testing monotonic trend", "topics": [ "Isotest" ] }, { "page": "IsoTest.nm", "title": "Calculate the value of the test statistics for testing monotonic trend", "topics": [ "IsoTest.nm" ] }, { "page": "nm400", "title": "NM-400 in vitro dataset", "topics": [ "nm400" ] }, { "page": "nmplot", "title": "Create plots of the dose and the response for each nanomaterial in the dataset", "topics": [ "nmplot" ] }, { "page": "nmplot.cat", "title": "Create plots of the dose and the response grouped by a variable", "topics": [ "nmplot.cat" ] }, { "page": "nmplot.n", "title": "Create plots of the dose and the response for every unique value of a certain variable", "topics": [ "nmplot.n" ] }, { "page": "nmplot.ncat", "title": "Create plots of the dose and the response differentiated by specified variables", "topics": [ "nmplot.ncat" ] }, { "page": "SplitData", "title": "Split the data of each nanomaterial into different subsets of data", "topics": [ "SplitData" ] }, { "page": "SubsetData", "title": "Create a subset of data", "topics": [ "SubsetData" ] } ], "_rundeps": [ "cli", "cpp11", "dplyr", "farver", "forcats", "generics", "ggplot2", "glue", "gridExtra", "gtable", "Iso", "isoband", "labeling", "lifecycle", "magrittr", "pillar", "pkgconfig", "purrr", "R6", "RColorBrewer", "rlang", "S7", "scales", "stringi", "stringr", "tibble", "tidyr", "tidyselect", "utf8", "vctrs", "viridisLite", "withr" ], "_score": 1, "_indexed": true, "_nocasepkg": "nmtox", "_universes": [ "rahmasarina" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.1.0", "date": "2026-05-28T07:49:36.000Z", "distro": "noble", "commit": "53eb4029a0172baca548a96e60b6e9d7c02a6bc2", "fileid": "17fcc6409e7892ac38df4a9f4a13ec1c3c34583a16d967cf86f20380a2596548", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/rahmasarina/actions/runs/26561726108" }, { "r": "4.6.0", "os": "linux", "version": "0.1.0", "date": "2026-05-28T07:50:01.000Z", "distro": "noble", "commit": 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